Sunitinib Malate

Overview

Sunitinib (SU 11248) Malat is a multi-targeted receptor tyrosine kinase inhibitor with IC 50 s of 80 nM and 2 nM for VEGFR2 and PDGFRβ , respectively. Sunitinib Malat, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation.

Application

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Product Information

• Catalog No.: HY-10255
• CAS No.: 341031-54-7
• Molecular Formula: C26H33FN4O7
• Molecular Weight: 532.56
• Purity: 99.74%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 2 years; -20°C, 1 year (sealed storage, away from moisture)
• Solubility: 10 mg/mL (18.78 mM); Suspended solution; Need ultrasonic and adjust pH to 5 with HCl
• Availability: In-stock

Source

Original product source