Sunitinib

Overview

Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC 50 s of 80 nM and 2 nM for VEGFR2 and PDGFRβ , respectively. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation.

Application

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Product Information

• Catalog No.: HY-10255A
• CAS No.: 557795-19-4
• Molecular Formula: C22H27FN4O2
• Molecular Weight: 398.47
• Purity: 99.04%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1.11 mg/mL (2.79 mM); Clear solution
• Availability: In-stock

Source

Original product source