Atecegatran

Overview

Atecegatran (AR-H067637) is an orally active competitive thrombin inhibitor with a K i of 2-4 nM. AR-H067637 inhibits platelet activation and aggregation by blocking thrombin binding to fibrin and thrombomodulin . Atecegatran demonstrates significant anticoagulant effects in various plasma coagulation assays, with an IC 50 ranging from 93 to 220 nM. Atecegatran can be used in research related to thromboembolic disorders.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Thrombin

Product Information

• Catalog No.: HY-10275
• CAS No.: 433937-74-7
• Molecular Formula: C21H21ClF2N4O4
• Molecular Weight: 466.87
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source