CMPD101 hydrochloride

Overview

CMPD101 hydrochloride is a novel membrane-permeable, small-molecule inhibitor of both GRK2 and GRK3 with IC 50 s of 18 nM and 5.4 nM, respectively. CMPD101 hydrochloride also inhibits Rho-associated kinase 2 ( ROCK-2 ) and PKCα ( IC 50 s =1.4 μM and 8.1 μM, respectively).

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > ROCK | Products > Signaling Pathways > PKC | Products > Signaling Pathways > G Protein-coupled Receptor Kinase (GRK)

Product Information

• Catalog No.: HY-103045A
• CAS No.: 1941168-71-3
• Molecular Formula: C24H22ClF3N6O
• Molecular Weight: 502.92
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source