EHNA hydrochloride

Overview

EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 ( PDE2 ) ( IC 50 =4 μM) and adenosine deaminase (ADA) . EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)( IC 50 :0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral , antitumour and antiarrhythmic effects.

Application

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Product Information

• Catalog No.: HY-103160A
• CAS No.: 58337-38-5
• Molecular Formula: C14H24ClN5O
• Molecular Weight: 313.83
• Purity: 99.67%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 2 years; -20°C, 1 year (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (6.63 mM); Clear solution
• Availability: In-stock

Source

Original product source