CGH2466 dihydrochloride

Overview

CGH 2466 dihydrochloride is an orally active adenosine A1, A2B and A3 receptor antagonist with the IC 50 values of 19 nM, 21 nM, and 80 nM respectively. CGH 2466 dihydrochloride inhibits p38 MAPK ( IC 50 = 187~ 400 nM) and phosphodiesterase type 4D ( IC 50 = 22 nM). CGH 2466 dihydrochloride displays potent anti-inflammatory effects both in vitro and in vivo, and can be used for research on asthma and chronic obstructive pulmonary disease (COPD).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Adenosine Receptor | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-103167
• CAS No.: 1177618-54-0
• Molecular Formula: C14H11Cl4N3S
• Molecular Weight: 395.13
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source