Trimetrexate glucuronate

Overview

Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia .

Application

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Product Information

• Catalog No.: HY-103396
• CAS No.: 82952-64-5
• Molecular Formula: C25H33N5O10
• Molecular Weight: 563.56
• Purity: 98.09%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 2.5 mg/mL (4.44 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source