AV-412 free base

Overview

AV-412 free base (MP-412 free base) is an EGFR inhibitor with IC 50 s of 0.75, 0.5, 0.79, 2.3, 19 nM for EGFR , EGFR L858R , EGFR T790M , EGFR L858R/T790M and ErbB2, respectively.

Application

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Product Information

• Catalog No.: HY-10346A
• CAS No.: 451492-95-8
• Molecular Formula: C27H28ClFN6O
• Molecular Weight: 507.00
• Purity: 98.10%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.93 mM); Clear solution
• Availability: In-stock

Source

Original product source