Canertinib

Overview

Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC 50 s of 7.4 and 9 nM. Canertinib is active against vaccinia virus respiratory infection in mice.

Application

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Product Information

• Catalog No.: HY-10367
• CAS No.: 267243-28-7
• Molecular Formula: C24H25ClFN5O3
• Molecular Weight: 485.94
• Purity: 99.74%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 1.25 mg/mL (2.57 mM); Clear solution
• Availability: In-stock

Source

Original product source