QC6352 (Standard)

Overview

QC6352 (Standard) is the analytical standard of QC6352 ( HY-104048 ). This product is intended for research and analytical applications. QC6352 is an orally active KDM4 inhibitor with anti-tumor and anti-proliferative activity. QC6352 has in vivo inhibitory effects on PDX models of breast and colon cancer and reduces the number of chemoresistant cell populations. QC6352 inhibits KDM4 different isoforms with IC 50 s of 104 nM (KDM4A), 56 nM (KDM4B), 35 nM (KDM4C), and 104 nM (KDM4D), respectively. QC6352 has moderate inhibitory activity against KDM5 with an IC 50 of 750 nM (KDM5B).

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Histone Demethylase

Product Information

• Catalog No.: HY-104048R
• CAS No.: 1851373-36-8
• Molecular Formula: C24H25N3O2
• Molecular Weight: 387.47
• Purity: 95%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source