Ki20227 (Standard)

Overview

Ki20227 (Standard) is the analytical standard of Ki20227 ( HY-10408 ). This product is intended for research and analytical applications. Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC 50 s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > c-Fms | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > c-Kit | Products > Signaling Pathways > PDGFR

Product Information

• Catalog No.: HY-10408R
• CAS No.: 623142-96-1
• Molecular Formula: C24H24N4O5S
• Molecular Weight: 480.54
• Purity: 95%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source