TAK-715

Overview

TAK-715 is an orally active and potent p38 MAPK inhibitor with IC 50 s of 7.1 nM, 200 nM for p38α and p38β , respectively. TAK-715 inhibits casein kinase I (CK1δ/ε) to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model.

Application

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Product Information

• Catalog No.: HY-10456
• CAS No.: 303162-79-0
• Molecular Formula: C24H21N3OS
• Molecular Weight: 399.51
• Purity: 99.76%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.26 mM); Clear solution
• Availability: In-stock

Source

Original product source