Atevirdine (U 87201E) mesylate is a nonnucleoside reverse transcriptase ( NNRT ) inhibitor. Atevirdine mesylate can inhibit human immunodeficiency virus type 1 ( HIV-1 ) with an IC 50 of 0.06-1.6 μM. Atevirdine mesylate shows highly synergistic effects against Zidovudine /Didanosine-resistant clinical isolates of HIV-1 companied with Zidovudine ( HY-17413 )/Didanosine (Hy-B0249). Atevirdine mesylate can be used for the research of AIDS.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Immunodeficiency Disease | Products > Disease Areas > AIDS | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > HIV | Products > Signaling Pathways > Reverse Transcriptase
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