Fandosentan potassium

Overview

Fandosentan potassium is a potent endothelin A receptor ( ET A R ) antagonist. Fandosentan potassium inhibits CYP2C9 and CYP3A4 activities with IC 50 values of 39.6 and 21.6 μM, respectively. Fandosentan potassium reverses the hypoxic pulmonary vasoconstriction in the perinatal lamb. Fandosentan potassium can be used for pulmonary hypertension research [1][2] .

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Pulmonary Hypertension | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Endothelin Receptor | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-105408A
• CAS No.: 221246-12-4
• Molecular Formula: C25H17F3KNO6S
• Molecular Weight: 555.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source