Sarpogrelate-d 4 (MCI-9042-d 4 ) hydrochloride is deuterium labeled Sarpogrelate (hydrochloride). Sarpogrelate hydrochloride (MCI-9042) is a selective 5-HT 2 R antagonist, with pK i s of 8.52, 6.57, and 7.43 for 5-HT 2A , 5-HT 2B , and 5-HT 2C receptors, respectively. Sarpogrelate hydrochloride displays selectivity over 5-HT 1 , 5-HT 3 , 5-HT 4 , α 1 -, α 2 - and β-adrenoreceptor, histamine H 1 , H 2 and muscarinic M 3 receptors. Sarpogrelate hydrochloride can be used for the research of vascular disease associated with thrombosis.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > 5-HT Receptor
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