Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic . Azidamfenicol inhibits ribosomal peptidyltransferase (K i =22 μM). Azidamfenicol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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