AGN 192870

Overview

AGN 192870 is a RAR neutral antagonist with K d s of 147, 33, and 42 nM for RARα, RARβ, and RARγ, respectively. AGN 192870 shows IC 50 s of 87 and 32 nM for RARαand RARγ, respectively. AGN 192870 shows RARβ partial agonism. AGN 192870 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Others | Products > Signaling Pathways > RAR/RXR

Product Information

• Catalog No.: HY-105689
• CAS No.: 166977-57-7
• Molecular Formula: C27H22O2
• Molecular Weight: 378.46
• Purity: 98.49%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1 mg/mL (2.64 mM); Clear solution
• Availability: In-stock

Source

Original product source