Diethyl methylphosphonate

Diethyl methylphosphonate
  • CAS No.:683-08-9
Other grades of this product :
Diethyl methylphosphonate Basic information
Product Name:Diethyl methylphosphonate
Synonyms:DEMP;Diethoxymethylphosphine oxide;diethylmethanephosphate;methyl-phosphonicacidiethylester;o,o-Diethyl methylphosphonate;Phosphonic acid, methyl-, diethyl ester;Phosphonicacid,methyl-,diethylester;METHYLPHOSPHONIC ACID DIETHYL ESTER
CAS:683-08-9
MF:C5H13O3P
MW:152.13
EINECS:211-667-4
Product Categories:C-C Bond Formation;Horner-Wadsworth-Emmons Reagents;Olefination
Mol File:683-08-9.mol
Diethyl methylphosphonate Chemical Properties
Boiling point 194 °C(lit.)
density 1.041 g/mL at 25 °C(lit.)
refractive index n20/D 1.414(lit.)
Fp 168 °F
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Liquid
color Clear colorless to pale yellow
Water Solubility Miscible with water.
BRN 1753416
Stability:Hygroscopic
CAS DataBase Reference683-08-9(CAS DataBase Reference)
NIST Chemistry ReferenceDiethyl methanephosphonate(683-08-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS SZ9085000
HS Code 29310095
MSDS Information
ProviderLanguage
Diethyl methylphosphonate English
SigmaAldrich English
ACROS English
ALFA English
Diethyl methylphosphonate Usage And Synthesis
Chemical Propertiesclear colorless liquid
UsesDiethyl methylphosphonate is used as a precursor for the synthesis of gem-difluroalkenyphosphonate via reaction with alpha-trifluromethylstyrene. It is also used in the synthesis of phosphonylated peptides, fluoroalkyl alpha- and beta-aminophosphonates, pyridone alkaloids with neuritogenic activity and lipophilic meropenem-derived prodrugs. It is readily mineralized by photoexcited titanium dioxide (TiO2).
Diethyl methylphosphonate Preparation Products And Raw materials
Raw materialsTETRAETHYL ETHYLENEDIPHOSPHONATE
Preparation ProductsMethyldiethoxyphosphine-->Methyl diethylphosphonoacetate-->ETHYL METHYLPHOSPHONIC ACID-->TETRAMETHYLSUCCINONITRILE-->Bromoethane

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