Pomisartan is an orally active angiotensin II receptor type AT1 antagonist ( IC 50 =0.26 μM). Pomisartan works by inhibiting the binding of angiotensin II to the AT1 receptor , thereby blocking the vasoconstriction and aldosterone release caused by this interaction. Pomisartan results in a blood pressure-lowering effect.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Angiotensin Receptor
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