PMX 53 monoacetate

Overview

PMX 53 monoacetate (3D53 monoacetate) is a potent orally active CD88 (C5aR) antagonist that inhibits C5a-induced neutrophil myeloperoxide release and chemotactic activity. PMX 53 monoacetate has an IC 50 value of 20 nM against C5a-induced neutrophil myeloperoxide release. >The value is 22 nM, and the IC 50 value of the chemotactic activity is 75 nM. PMX 53 monoacetate is also an agonist of MrgX2.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-106178D
• CAS No.: 852629-88-0
• Molecular Formula: C49H69N11O9
• Molecular Weight: 956.14
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source