Niraparib tosylate

Overview

Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC 50 of 3.8 and 2.1 nM, respectively. Niraparib tosylate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Application

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Product Information

• Catalog No.: HY-10619B
• CAS No.: 1038915-73-9
• Molecular Formula: C26H28N4O4S
• Molecular Weight: 492.59
• Purity: 99.99%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (5.08 mM); Clear solution
• Availability: In-stock

Source

Original product source