Niraparib Tosylate (Standard)

Overview

Niraparib Tosylate (Standard) is the analytical standard of Niraparib Tosylate ( HY-10619B ). This product is intended for research and analytical applications. Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC 50 of 3.8 and 2.1 nM, respectively. Niraparib tosylate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > PARP | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-10619BR
• CAS No.: 1038915-73-9
• Molecular Formula: C26H28N4O4S
• Molecular Weight: 492.59
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source