SB 247083 is a selective, competitive and orally active endothelin-A receptor antagonist with a K i of 0.41 nM. SB 247083 shows a K i of 467 nM to endothelin-B receptor . SB 247083 shows a K b of 3.5 nM for ET-1-induced contraction of rat aorta. SB 247083 can be used for the research of cardiovascular disease .
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Endothelin Receptor
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