Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine ( HY-17589A ) sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC 50 s of 0.9 nM and 20.8 nM, respectively.
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