Girolline

Girolline
  • CAS No.:110883-46-0
  • Grade:99.98%
  • Formula:C6H11ClN4O
  • M.W.:190.63

Overview

Girolline (RP 49532) is a protein synthesis inhibitor and a functional modulator of eIF5A . Girolline induces ribosome stalling by interfering with the binding of eIF5A to ribosomes. Girolline also inhibits the production of IL-6 and IL-8 , and induces cell cycle arrest in tumor cells. Girolline is applicable to research related to inflammatory diseases, solid tumors, leukemia and malaria.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > AP-1 | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > Apoptosis

Product Information

  • Catalog No.: HY-106801
  • CAS No.: 110883-46-0
  • Molecular Formula: C6H11ClN4O
  • Molecular Weight: 190.63
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Availability: In-stock

Source

Original product source


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