3′-Azido-2′,3′-dideoxyuridine

Overview

3′-Azido-2′,3′-dideoxyuridine (AzdU) is a nucleoside analog of Zidovudine ( HY-17413 ). 3′-Azido-2′,3′-dideoxyuridine is a potent inhibitor of human immunodeficiency virus ( HIV ) replication in human peripheral blood mononuclear cells (PBMC) with limited toxicity for human bone marrow cells (BMC). 3′-Azido-2′,3′-dideoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > HIV

Product Information

• Catalog No.: HY-106850
• CAS No.: 84472-85-5
• Molecular Formula: C9H11N5O4
• Molecular Weight: 253.21
• Purity: 99.59%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (8.21 mM); Clear solution
• Availability: In-stock

Source

Original product source