E4177

Overview

E4177 (57G709) is an orally active angiotensin II receptor antagonist. E4177 can inhibit the growth of vascular smooth muscle cells (HASMC) and the increase of cell surface area. In addition, E4177 can also increase the expression of platelet-derived growth factor ( PDGF ) receptor. E4177 can be used in the study of vascular diseases.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Angiotensin Receptor | Products > Signaling Pathways > PDGFR

Product Information

• Catalog No.: HY-106890
• CAS No.: 135070-05-2
• Molecular Formula: C24H21N3O2
• Molecular Weight: 383.44
• Purity: 98.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.52 mM); Clear solution
• Availability: In-stock

Source

Original product source