Amustaline dihydrochloride

Overview

Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products).

Application

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Product Information

• Catalog No.: HY-106991A
• CAS No.: 210584-54-6
• Molecular Formula: C22H27Cl4N3O2
• Molecular Weight: 507.28
• Purity: 95.0%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (4.93 mM); Clear solution
• Availability: In-stock

Source

Original product source