tert-Butyl nitrite

CAS No.：540-80-7

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Other grades of this product :

boiling point	61-63 °C(lit.)
density	0.867 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.368(lit.)
flash point	−10 °F
Storage conditions	2-8°C
solubility	alcohol: very soluble(lit.)
form	Liquid
colour	Clear yellow
Water solubility	slightly soluble
Merck	14，1583
BRN	1209339
CAS	540-80-7
NIST Chemical information	(CH3)3CONO(540-80-7)

tert-Butyl nitrite is employed as a reagent for diazotization and nitrosation of alcohols, thiols, amines and cycloalkanes. It plays an important role in photocatalyzed conversion of aryl and heteroarylamines to selenides. It finds application in the preparation of aryl azides from aryl amines. It is also useful for radical multifunctionalization reactions of aliphatic alkenes and source of nitric oxide.

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