Selamectin

Selamectin
  • CAS No.:220119-17-5
  • Grade:99.31%
  • Formula:C43H63NO11
  • M.W.:769.96
  • Solvent:≥ 2.5 mg/mL (3.25 mM); Clear solution

Overview

Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm , Lymphatic filariae , and nematode infection . Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC 50 of 120 nM.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Infection | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > Chloride Channel | Products > Signaling Pathways > P-glycoprotein | Products > Signaling Pathways > Bacterial

Product Information

  • Catalog No.: HY-107212
  • CAS No.: 220119-17-5
  • Molecular Formula: C43H63NO11
  • Molecular Weight: 769.96
  • Purity: 99.31%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
  • Solubility: ≥ 2.5 mg/mL (3.25 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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