Ancriviroc

Overview

Ancriviroc (SCH-351125) is an orally active CCR5 antagonist with an IC 50 value of 13 nM against hCCR5 . Ancriviroc specifically binds to hCCR5, blocks ligand-induced signal transduction, calcium influx, GTPγS binding, chemotaxis, ligand binding, and HIV-1 entry, induces conformational changes in CCR5 , and inhibits infection and replication of R5-tropic HIV-1 .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > HIV Infection | Products > Disease Areas > Sexually Transmitted Disease | Products > Disease Areas > HIV-1 Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Infection | Products > Signaling Pathways > HIV | Products > Signaling Pathways > CCR | Products > Signaling Pathways > Calcium Channel

Product Information

• Catalog No.: HY-107401
• CAS No.: 370893-06-4
• Molecular Formula: C28H37BrN4O3
• Molecular Weight: 557.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source