8-pCPT-2′-O-Me-cAMP sodium

Overview

8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP) sodium, an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac) . 8-pCPT-2′-O-Me-cAMP sodium activates Epac1 ( EC 50 = 2.2 μM), but not PKA (EC 50 >10 μM). 8-pCPT-2′-O-Me-cAMP sodium stimulates Epac-mediated Ca 2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP sodium is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP sodium enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-107543
• CAS No.: 634207-53-7
• Molecular Formula: C17H16ClN5NaO6PS
• Molecular Weight: 507.82
• Purity: 99.81%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (4.10 mM); Clear solution
• Availability: In-stock

Source

Original product source