PD 128042

Overview

PD 128042 (CI 976) is a potent, orally active, and selective inhibitor of ACAT (acyl coenzyme A:cholesterol acyltransferase ) with an IC 50 s of 73 nM. PD 128042 is also a potent LPAT (lysophospholipid acyltransferase ) inhibitor. PD 128042 inhibits Golgi-associated LPAT activity (IC 50 =15 μM). PD 128042 inhibits multiple membrane trafficking steps, including ones found in the endocytic and secretory pathway.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Acyltransferase

Product Information

• Catalog No.: HY-107572
• CAS No.: 114289-47-3
• Molecular Formula: C23H39NO4
• Molecular Weight: 393.56
• Purity: 99.97%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source