BIO5192

Overview

BIO5192 is a selective and potent integrin α4β1 (VLA-4) inhibitor ( K d <10 pM). BIO5192 selectively binds to α4β1 ( IC 50 =1.8 nM) over a range of other integrins. BIO5192 results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Integrin

Product Information

• Catalog No.: HY-107589
• CAS No.: 327613-57-0
• Molecular Formula: C38H46Cl2N6O8S
• Molecular Weight: 817.78
• Purity: 99.96%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (3.06 mM); Clear solution
• Availability: In-stock

Source

Original product source