BMS-344577 (Compound 22) is a potent and orally active factor Xa inhibitor ( IC 50 = 4 nM, EC2xPT = 7 μM). BMS-344577 shows potent CYP3A4 inhibition activity ( IC 50 = 0.3 μM). BMS-344577 can be used for the research of cardiovascular disease .
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Factor Xa | Products > Signaling Pathways > Cytochrome P450
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