5-Acetylsalicylic acid is the derivate of Aspirin ( HY-14654 ), with anti-inflammatory property. 5-Acetylsalicylic acid is the active metabolite of Sulfasalazine ( HY-14655 ) and its production is regulated by beneficial bacteria in the gut but is confined to the intestinal tract. 5-Acetylsalicylic acid exhibits a mild cytotoxicity effect on B16F10 cells. 5-Acetylsalicylic acid can be used for the study of inflammatory bowel disease (IBD) such as ulcerative colitis (UC).
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