HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD 2 , and acts as an anti-allergic agent, with a K d of 0.8 μM and an IC 50 of 6 μM. Shows no obvious effect on COX-1 , COX-2 , m-PGES, or L-PGDS.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PGE synthase
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