CS-2100 (Compound 10b) is a potent, selective, orally active and S1P 3 -sparing S1P 1 agonist with an EC 50 of 4.0 nM for human S1P 1 . CS-2100 shows in vivo immunosuppressive efficacy in rats with an ID 50 (infective dose) of 0.407 mg/kg for HvGR.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > LPL Receptor
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