CYM50308

Overview

CYM50308 (ML248) is a potent, selective and high affinity sphingosine-1-phosphate receptor 4 (S1P 4 -R) agonist with an EC 50 of 56 nM. CYM50308 displays 37-fold more selective for S1P 4 -R than S1P 5 -R. CYM50308 has no activity at S1P 1 -R, S1P 2 -R and S1P 3 -R subtypes at concentrations up to 25 μM.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > LPL Receptor

Product Information

• Catalog No.: HY-108495
• CAS No.: 1345858-76-5
• Molecular Formula: C20H21F2N3O2S
• Molecular Weight: 405.46
• Purity: 98.0%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 3 mg/mL (7.40 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source