Q94 hydrochloride

Overview

Q94 hydrochloride, a selective PAR 1 antagonist ( IC 50 =916 nM), can selectively block PAR 1 / Gαq interaction and signalling. Q94 hydrochloride blocks PAR 1 -mediated increases in both CCL2 mRNA and protein levels in a dose-dependent manner. Q94 hydrochloride also completely blocks thrombin-induced ERK1/2 and MLC phosphorylation.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Others | Products > Signaling Pathways > Protease Activated Receptor (PAR)

Product Information

• Catalog No.: HY-108554
• CAS No.: 1052076-77-3
• Molecular Formula: C21H18Cl2N2
• Molecular Weight: 369.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source