WAY-362692

Overview

WAY-362692 is a secreted frizzled-related protein ( sFRP-1 ) inhibitor ( IC 50 of 0.02 μM), targeting the netrin domain of sFRP-1 . WAY-362692 can competitively inhibit the interaction between sFRP-1 and Wnt proteins, and activate the Wnt/β-catenin signaling pathway ( EC 50 = 0.03 μM). WAY-362692 can activate osteoblasts and promote bone remodeling. WAY-362692 can be used for the research of metabolic disease , such as osteoporosis.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > sFRP-1 | Products > Signaling Pathways > Wnt | Products > Signaling Pathways > β-catenin

Product Information

• Catalog No.: HY-10860
• CAS No.: 915763-27-8
• Molecular Formula: C28H35F3N4O6S2
• Molecular Weight: 644.73
• Purity: 99.91%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (3.88 mM); Clear solution
• Availability: In-stock

Source

Original product source