PPNDS tetrasodium is a selective and competitive meprin β inhibitor ( IC 50 : 80 nM, K i : 8 nM), and also inhibits ADAM10 ( IC 50 : 1.2 μM). PPNDS tetrasodium is also a P2X1 receptor antagonist. PPNDS is an agonist for the ATP receptor of Paramecium . PPNDS tetrasodium potently inhibits polymerases from viruses. PPNDS tetrasodium can be used in the research of infection and cancers.
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