SB-334867 (Standard)

SB-334867 (Standard)
  • CAS No.:249889-64-3
  • Grade:98%
  • Formula:C17H14ClN5O2
  • M.W.:355.78

Overview

SB-334867 (Standard) is the analytical standard of SB-334867. This product is intended for research and analytical applications. SB-334867 (SB 334867A) is an excellent,selective and blood-brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Others | Products > Research Areas > Endocrinology | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Orexin Receptor (OX Receptor) | Products > Signaling Pathways > Reference Standards

Product Information

  • Catalog No.: HY-10895R
  • CAS No.: 249889-64-3
  • Molecular Formula: C17H14ClN5O2
  • Molecular Weight: 355.78
  • Purity: 98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Availability: In-stock

Source

Original product source


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