Nacubactam

Overview

Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and C β-lactamases. Nacubactam acts as a penicillin binding protein (PBP) 2-active antibacterial , and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs. Nacubactam potentiates the antimicrobial activities of Piperacillin ( HY-B1923 ), Cefepime ( HY-B0692 ), and Meropenem ( HY-13678 ) against CTX-M-15-positive Escherichia coli and KPC-positive Klebsiella pneumoniae .

Application

Products | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Beta-lactamase | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-109008
• CAS No.: 1452458-86-4
• Molecular Formula: C9H16N4O7S
• Molecular Weight: 324.31
• Purity: 99.43%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.08 mg/mL (6.41 mM); Clear solution
• Availability: In-stock

Source

Original product source