Praliciguat (Standard) is the analytical standard of Praliciguat ( HY-109039 ). This product is intended for research and analytical applications. Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase (sGC) activator. Praliciguat can increases cGMP via the nitric oxide (NO)-sGC pathway. Praliciguat can inhibit the expression of proinflammatory cytoK i nes and inhibit apoptosis . Praliciguat can promote vasodilation. Praliciguat can be used for the researches of metabolic disease and cardiovascular disease , such as hypertension, diabetes and heart failure.
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