Quilseconazole

CAS No.：1340593-70-5
Grade：98.61%
Formula：C22H14F7N5O2
M.W.：513.37
Solvent：2.5 mg/mL (4.87 mM); Suspended solution; Need ultrasonic

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

Quilseconazole (VT-1129) is an orally active, highly selective fungal cytochrome P450 enzyme Cyp51 inhibitor that can cross the blood-brain barrier. Quilseconazole prevents the synthesis of ergosterol, an important component of the fungal cell membrane, by inhibiting Cyp51 . Quilseconazole has minimal effects on human CYP enzymes . Quilseconazole has antifungal activity and can be used in the study of cryptococcal meningitis and other diseases .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Fungal Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Cytochrome P450

Product Information

Catalog No.: HY-109040
CAS No.: 1340593-70-5
Molecular Formula: C22H14F7N5O2
Molecular Weight: 513.37
Purity: 98.61%
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Solubility: 2.5 mg/mL (4.87 mM); Suspended solution; Need ultrasonic
Availability: In-stock

Source

Original product source

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