Quilseconazole

Overview

Quilseconazole (VT-1129) is an orally active, highly selective fungal cytochrome P450 enzyme Cyp51 inhibitor that can cross the blood-brain barrier. Quilseconazole prevents the synthesis of ergosterol, an important component of the fungal cell membrane, by inhibiting Cyp51 . Quilseconazole has minimal effects on human CYP enzymes . Quilseconazole has antifungal activity and can be used in the study of cryptococcal meningitis and other diseases .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Fungal Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-109040
• CAS No.: 1340593-70-5
• Molecular Formula: C22H14F7N5O2
• Molecular Weight: 513.37
• Purity: 98.61%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (4.87 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source