Icenticaftor

Overview

Icenticaftor (QBW251) is an orally active CFTR channel potentiator, with EC 50 s of 79 nM and 497 nM for F508del and G551D CFTR , respectively. Icenticaftor can be used for chronic obstructive pulmonary disease (COPD) and cystic fibrosis research.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > CFTR

Product Information

• Catalog No.: HY-109177
• CAS No.: 1334546-77-8
• Molecular Formula: C12H13F6N3O3
• Molecular Weight: 361.24
• Purity: 99.66%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 4.25 mg/mL (11.77 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source