3-Mercapto-1,2-propanediol

3-Mercapto-1,2-propanediol
  • CAS No.:96-27-5

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
melting point<25 °C
boiling point118 °C5 mm Hg(lit.)
density1.25 g/mL at 25 °C(lit.)
Vapor pressure<1 hPa (20 °C)
Refractive indexn20/D 1.527(lit.)
flash point>230 °F
Storage conditions2-8°C
solubilityabsolute ethanol: 1 mL/mL
pkapK1:9.43 (25°C,μ=0.5)
formLiquid
colourClear colorless to yellow
OdorStench odour
PH3.5-7.0
Water solubilityslightly soluble
susceptibilityAir Sensitive & Hygroscopic
Merck14,9335
BRN1732046
InChIKeyPJUIMOJAAPLTRJ-UHFFFAOYSA-N
CAS96-27-5
EPA Chemical Information1,2-Propanediol, 3-mercapto- (96-27-5)
NIST Chemical informationMonothioglycerol(96-27-5)


1-Thioglycerol is a reagent used in fluorescence, spectroscopy, and microbiology techniques. Varying the concentration of 1-thioglycerol in the preparation of CdSe/CdS core-shell ultrasmall quantum dots (CS-USQDs) allows a precise way to control the size of the shell, with shell size increasing with increased concentration. It is used as a capping agent in the synthesis of nanocrystals analyzed via Raman and UV/Vis spectroscopy. Biologically, 1-thioglycerol stimulates porphyrin synthesis and increases glutamyl-tRNA reductase activity in E. coli grown in an aerobic environment. It was previously a component in hair permanents used to produce waves or curls

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