GPR120 Agonist 5 (compound 12) is an agonist targeting GPR120 ( EC 50 =1.2 μM). GPR120 Agonist 5 promotes the release of glucagon-like 1 ( GLP-1 ) by binding to the GPR120 receptor, which in turn binds to its receptors on pancreatic beta cells, increasing insulin secretion and thereby lowering blood sugar levels. GPR120 Agonist 5 also helps reduce chronic low-grade inflammation, which plays an important role in the pathogenesis of obesity, insulin resistance, and type 2 diabetes. GPR120 Agonist 5 can be used to investigate the mechanism of action of GPR120 in metabolic and inflammatory diseases.
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