Trametinib- 13 C,d 3 is the 13 C- and deuterium labeled Trametinib. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC 50 s of about 2 nM. Trametinib activates autophagy and induces apoptosis .
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > MEK | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis
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